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Furosemide Manufacturing United Kingdom and USA
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Furosemide

  • Product Name : Furosemide
  • Grade : IP / BP / USP
  • Therapeutic Category : Diuretic
  • CAS No : 54-31-9
  • COA : Available
  • MSDS : Available

Description

Furosemide is a loop diuretic inhibitor of NKCC (Na+/2Cl-/K+) cotransporter. Furosemide acts as a non-competitive antagonist at GABAA receptors with ~ 100-fold greater selectivity for α6-containing receptors than α1-containing receptors.

 Furosemide is primarily used for the treatment of hypertension and edema. It is the first-line agent in most people with edema caused by congestive heart failure. It is also used for hepatic cirrhosis, renal impairment, nephrotic syndrome, in adjunct therapy for cerebral or pulmonary edema where rapid diuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration.

 

Specification:

ITEMS

SPECIFICATION

Appearance

White or almost white powder

Identification

Meets the requirements

Solubility

Practically insoluble in water methylene chloride, sparingly soluble in alcohol, slightly soluble in ether, soluble in acetone

Melting Point

About 210

Loss on Drying

≤0.5%

Sulphated Ash

≤0.1%

Chloride

≤0.02%

Heavy Metals

≤20ppm

Sulfate

≤10ppm

Related Substances

≤0.5%

Assay

98.5 ~ 101.0%

Standard

BP2002

 

Packaging details:

 

Packaging details:

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage:

Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life:

5 years if sealed and store away from direct sun light.

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